SAA-C03 Design high-performing architectures

A bioinformatics workload requires maximum single-threaded CPU performance for a genomic sequencing algorithm, with jobs that run 2–4 hours. Which EC2 instance family fits best?

Show answer and explanation

Answer: B

Compute-optimized C-family instances exist exactly for CPU-bound jobs, and C7g adds Graviton3 cores, which deliver strong per-core performance and very attractive performance per dollar for repeatable batch-style runs in the 2–4 hour range.

GPU instances help parallel matrix work, not single-threaded code, and memory-optimized instances pay for memory capacity the algorithm does not need.

Why the other options are wrong

  • A. M-family general-purpose instances strike a balance between CPU and memory, so they cost more per core and give up throughput for memory the genomic workload does not use.
  • C. R-family instances are built around large memory capacity — the profile of in-memory databases and caches, not a CPU-bound single-threaded algorithm.
  • D. P4d GPUs accelerate massively parallel matrix operations like deep learning training; a single-threaded sequencing loop gains almost nothing from them.

Keep going. 203 SAA-C03 questions, answers explained after each one.

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Reviewed November 2026. Spotted a problem with this question? Report it from the practice tool.